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American Association of Critical-Care Nurses

Official Patient and Family website of the Society of Critical Care Medicine ICU Medical Conditions 
 

Sepsis

Definition
Sepsis is a condition that starts with a widespread infection throughout the body and grows to life threatening condition. In sepsis, the body's response to the infection creates a new problem, one that traditional antibiotics are unlikely to treat.  Persons at risk for sepsis include those who have experienced trauma and those with chronic disease, low immune function, recent surgery and those with large wounds. Symptoms of sepsis include fever, rapid heart rate and rapid breathing. In more severe cases, blood pressure drops and shock may occur.
 
Causes
The cause of sepsis is unknown.  While we are learning more about sepsis all the time, we do not know why it occurs.  We do know if follows an infection.  The most important way to stop sepsis is to prevent infections. 
 
Treatment
An international effort is underway to treat sepsis (the Surviving Sepsis Campaign).  Therapies such as treating the infection with appropriate antibiotics are essential for success.   New treatments like Xigris (activated protein C) and goal directed therapy are promising.  Rapid treatment is urgent in sepsis.  The longer treatment is delayed, the less likely sepsis can be treated effectively.  
 
Comments
Sepsis can be very dangerous even when optimally treated. Sepsis can lead to widespread organ damage and organ failure making it one of the most common causes of death in ICU patients.
 
Related Links
 Sepsis Alliance - this web site is created for the public, to learn more about sepsis, how to prevent sepsis and the best treatment options.

Sepsis.com
This web site is produced by Eli Lilly, a pharmaceutical company that develops therapies for treating sepsis.


National Library of Medicine
The National Library of Medicine presents information and pictures about sepsis.


Surviving Sepsis Campaign                                                       The Surviving Sepsis Campaign is an international effort designed to improve outcome in patients with sepsis

 


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